The Next Ice Age Began Under the Roman Empire, Researchers Say, Until Global Warming Stopped It


A nurse-led chronic disease management clinic in the urology department of a tertiary hospital recorded 14,013 outpatient registrations between July 2024 and September 2026, according to a single-center retrospective descriptive study using routinely collected service records. The clinic primarily supported long-term management of patients with prostate and bladder cancer while also providing specialty nursing services for other urological conditions. Its follow-up system marked 3,547 of 3,553 assigned tasks as successful, a task-level success rate of 99.83%. These figures describe service activity and record completion; the study did not measure whether the clinic improved clinical outcomes or economic performance.
The clinic was established in July 2024 within the hospitalβs existing specialty nursing outpatient service framework. Its operating model included staffing and qualification requirements, professional training, clearly defined nursing responsibilities, physicianβnurse collaboration, standardized procedures, information-system support and quality management. Nurses worked within their authorized scope of practice, while urologists participated in medical assessment and treatment decisions when required. The service had four reported components: patient assessment and follow-up planning; treatment follow-up and adverse-event monitoring; rehabilitation guidance and health promotion; and assistance with healthcare policies and basic nursing care.
Monthly registrations increased from 147 in July 2024 to a peak of 710 in August 2026, with fluctuations during the reporting period. Total registration fees were CNY 152,758. The clinic delivered 14,246 prostate cancer-related injections, 3,523 urinary catheterizations, 2,777 intravesical instillation procedures and 2,142 urinary catheter removals. It also assisted patients with prostate or bladder cancer in applying for outpatient chronic and special disease insurance benefits. The study reports these counts as routine service activities, but it did not compare the procedures with those delivered elsewhere or evaluate their individual clinical effects.
Follow-up management was integrated into the clinicβs information system, which contained records for 1,111 patients. Of these, 953 patients had been followed up and 951 had successful follow-up records. Nurses also executed 3,553 follow-up tasks, of which 3,547 were successful, corresponding to the reported 99.83% task-level rate. The descriptive data do not specify the duration or effectiveness of patient follow-up, assess whether missed contacts influenced treatment adherence or health outcomes, or establish how the results would compare with another care model.
Because the research covered one tertiary hospital and relied on routinely collected records, it cannot establish how the clinic would operate in smaller facilities, under different staffing arrangements or in other health systems. The findings offer a documented example of a nurse-led outpatient service with defined responsibilities, standardized workflows, follow-up documentation and collaboration with urologists. The authors stated that further research is needed to evaluate the modelβs clinical outcomes and economic implications. Accordingly, the registration growth, procedural workload and high proportion of completed follow-up tasks should be interpreted as descriptions of implementation and recorded service delivery, not as evidence of improved survival, fewer complications, lower costs or other patient benefits.
Subject of Research: Operation and service activity of a nurse-led chronic disease management clinic in hospital urology
Article Title: Development and implementation of a nurse-led chronic disease management clinic in the urology department of a tertiary hospital: a descriptive study
Article References: Liu, C., Xia, Y., Jia, X., Wang, R., Li, T., Ma, Y., & Long, H. (2026). Development and implementation of a nurse-led chronic disease management clinic in the urology department of a tertiary hospital: a descriptive study. BMC Nursing. https://doi.org/10.1186/s12912-026-05566-z
Image Credits: AI Generated
DOI: 10.1186/s12912-026-05566-z
Keywords: nurse-led care, urology, outpatient nursing, chronic disease management, prostate cancer, bladder cancer, patient follow-up, service implementation, descriptive study, Development, implementation, nurse-led
A survey-based study of 246 village-level social welfare data operators found that business architecture, cross-organizational collaboration and technological readiness were positively and statistically significantly associated with perceived e-government integration impact in two Indonesian regencies. The research, focused on Gunung Kidul and Bangkalan, examined organizational, institutional, relational and technological capabilities associated with social welfare data integration. Governance and leadership and information policy did not show statistically significant direct relationships with perceived integration impact in the pooled sample.
The authors analyzed the survey with partial least squares structural equation modeling. In their framework, e-government integration impact, or EGII, represents perceived improvements in information, system and service quality, responsiveness and public trust. E-government integration scope, or EGIS, describes the breadth of integration across data, applications, electronic communication and knowledge-sharing processes.
EGII was strongly associated with EGIS, meaning that operators reporting more favorable perceived integration outcomes also tended to report broader integration. Because this was an observational analysis of survey responses, the results establish statistical relationships rather than causal effects. The findings identify three capabilities with significant direct relationships to EGII in the pooled model: business architecture, cross-organizational collaboration and technological readiness.
The evidence does not provide operational definitions for these constructs, but the results show that their measured levels were associated with respondentsβ assessments of e-government integration outcomes. By contrast, governance and leadership and information policy had no statistically significant direct relationships with EGII in that analysis. This absence of a detected direct relationship does not establish that the two factors are unimportant or that they operate only through indirect pathways, because the supplied findings do not report such indirect effects.
A regency-based robustness analysis found that some relationships were sensitive to local implementation conditions. Significant differences between Gunung Kidul and Bangkan were reported for the technological-readiness-to-EGII relationship and the EGII-to-EGIS relationship. The geographic comparison therefore cautions against assuming that the same capability relationships apply uniformly across the two regencies, although it does not identify the specific local practices responsible for those differences.
Its direct contribution is to show which measured interoperability capabilities were associated with perceived integration impact in the surveyed population, alongside evidence that some relationships varied between the two regencies.
Subject of Research: Survey-based analysis of interoperability capabilities for social welfare data integration in two Indonesian regencies
Article Title: Determinants of E-government interoperability capabilities for social welfare data integration in Gunung Kidul and Bangkalan Regencies, Indonesia
Article References: Fikri, R., Purnomo, E. P., Pribadi, U., Mohamed, A. M., & Mohammad, N. B. (2026). Determinants of E-government interoperability capabilities for social welfare data integration in Gunung Kidul and Bangkalan Regencies, Indonesia. Discover Sustainability. https://doi.org/10.1007/s43621-026-04608-5
Image Credits: AI Generated
DOI: 10.1007/s43621-026-04608-5
Keywords: social welfare data, e-government, interoperability, Indonesia, PLS-SEM, technological readiness, cross-organizational collaboration, business architecture, digital governance, public services, Determinants, capabilities
Women surveyed about their treatment for hyperemesis gravidarum, a severe form of nausea and vomiting during pregnancy, reported delayed or missed diagnoses, inadequate clinician knowledge of treatment guidelines, denied or discontinued medicines, and structural barriers restricting access to appropriate care. The qualitative study of 189 women, published in the Journal of Pharmacy Practice and Research, found that these experiences accompanied enduring emotional and psychological effects, including anxiety and post-traumatic stress syndrome. Associate Professor Luke Grzeskowiak, who led the research team at Flinders University, said the condition affects almost 4% of pregnancies.
The survey identified several issues affecting how hyperemesis gravidarum is recognised and treated. Participants described clinicians who lacked suitable training to diagnose the condition and who were either unaware of clinical management guidelines or did not follow them. Some women said they were not diagnosed with hyperemesis gravidarum when they should have been, while others reported receiving a diagnosis only late in the course of their illness. Other participants said health professionals denied prescribing or dispensing medications. The researchers also identified educational and financial status as possible influences on treatment outcomes, together with systemic barriers within Australiaβs healthcare system.
Misinformation about medicine safety further disrupted care for some participants. Some women said they stopped taking medication after reading reported safety concerns that the researchers said were not aligned with current research and management guidelines. Participants also described poor management of medication side effects, including constipation and mood disorders. Current treatment focuses on supportive care and on medicines, including antiemetics, that address nausea and vomiting. Nevertheless, women reported that their symptoms were often not taken seriously and that clinicians in several professions commonly lacked appropriate education and training to recognise and manage hyperemesis gravidarum.
The study documented emotional and psychological effects during and after the illness. Participants cited impaired quality of life, anxiety and post-traumatic stress syndrome. The researchers said some women reported that hyperemesis gravidarum influenced their decision to terminate an otherwise wanted pregnancy, while others said the trauma of a previous episode left them afraid to consider another pregnancy. Collectively, the researchers proposed improving experiences and outcomes through better education for health practitioners, greater public awareness, clearer clinical practice guidelines, expanded outpatient care, investment in specialist hyperemesis gravidarum clinics and services, changes to the Pharmaceutical Benefits Scheme, and strategies to improve medicine availability and affordability. Because the research was a qualitative survey based on reported experiences and perceptions, it does not quantify how frequently these barriers occur among all pregnancies affected by the condition.
Subject of Research: Womenβs experiences of pharmacological care for hyperemesis gravidarum
Article Title: Greater access to help needed for women with nausea during pregnancy
Article References: Greater access to help needed for women with nausea during pregnancy. Original publication (Bibliographic details unavailable.)
Image Credits: AI Generated
DOI: Not provided
Keywords: hyperemesis gravidarum, pregnancy, nausea and vomiting, antiemetic medicines, qualitative survey, clinical guidelines, healthcare access, medication safety, mental health, Greater, access, help