As much as half of the human genome is composed of so-called "jumping genes." These DNA sequences can make copies of themselves that are inserted back into the genome at another location, playing a significant functional role in creating the diversity that drives evolution and in regulating how other genes are turned on or off.
Penn State study identifies new regulator of jumping genes
Researchers at Weill Cornell Medicine have identified a molecular pathway that contributes to the death of insulin-producing beta cells in the pancreas.
Blocking specific proteins protects beta cells om excessive cellular stress
Biological clocks coordinate the spatiotemporal organization of metabolism with diurnal time cues, and bulk-tissue RNA sequencing studies in mammals have revealed widespread circadian (about 24 h) gene expression in mice and non-human primates.
Study shows circadian rhythms vary across different cell types
A new paper from the Equality, Diversity and Inclusion Committee and the Early Career Network of the European Sleep Research Society warns that sleep health is becoming a growing public health challenge across Europe and is calling for coordinated action to protect it.
Researchers call for coordinated action to protect European sleep health
Chemotherapy selectivity is limited by systemic toxicity. pH‑sensitive nanocarriers exploit tumor acidity as a release trigger but respond passively to a modest, heterogeneous gradient.
Glucose priming may improve tumor targeting for chemotherapy nanocarriers
Neurodevelopmental, psychiatric, and neurodegenerative disorders are traditionally studied separately yet show overlapping disturbances in neural regulation and resilience.
Women in the United States can expect to provide seven years of care over their lifetimes to aging family members or friends-up from six in 2011, University of Michigan research shows.
Women provide more lifetime elder care than men, study shows
Coeliac disease is an autoimmune condition in which the immune system reacts adversely to gluten. Eating gluten causes inflammation in the gut, which can damage the intestine and impair its ability to absorb nutrients.
Blood proteins may offer new clues to gut health in coeliac disease
Neuroblastoma is the most common solid tumor found outside of the brain in children, yet why some children respond well to treatment while others do not has remained poorly understood.
Scientists identify the neuroblastoma cells that signal poor outcomes
Two major international studies are providing new insight into how human milk is regulated, showing that some components respond to maternal nutrition, while others remain stable or reflect biological processes involved in lactation and infant growth.
New research reveals the remarkable complexity of human milk
Tardigrades, also called water bears, are famous for their ability to survive nearly anything. They protect themselves in extreme environments using proteins that researchers have developed into an efficient and effective strategy to preserve human red blood cells.
A trick from tardigrades could help human blood withstand freezing
ASTM International’s medical and surgical devices committee (F04) has approved a new standard that provides details and considerations for planning and conducting a seal zone leakage assessment for stent grafts.
ASTM International approves new surgical device standard
n6, maker of the icon96™ and icon16 thermocyclers powered by iconPCR™ with AutoNorm intelligent normalization technology for next‑generation sequencing (NGS) library preparation, today announced new and expanded distribution partnerships that significantly increase access to its instruments across Europe, the Middle East, and Africa.
n6 expands global distribution footprint, bringing iconPCR™ and AutoNorm to more scientists across Europe, the Middle East, and Africa
Researchers have shown that prenatal training may reduce the risk of postnatal depression in women, - but only if they have previously had a baby. This surprising finding is presented for the first time at the ECNP Congress in Munich.
Prenatal training may reduce postpartum depression risk in women with previous births
A new research project at the University of California, Riverside, has received funding to investigate whether a novel protein-based therapy can correct abnormal brain activity associated with Fragile X syndrome.
New project aims to test a protein-based therapy for Fragile X syndrome
A common blood test already carried out during routine health checks may contain clues about a person's long-term risk of dementia, according to research being presented at the ECNP Congress in Munich and recently published in the Journal of Alzheimer's Disease.
Routine blood test may offer clues to future dementia risk