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Additive manufacturing of ultralong and architected single crystals

By: Changmeng Liu · Yinan Cui · Jiachen Wang · Xiao Han · Zhongao Ji · Zhun Liang · Chongle Zhang · Jaime Marian · Zixiang Li · Tao Lu · Tianqiu Xu · Jinyu Zhang · Wei Cui · Wei Liu · Daining Fang · Y. Morris Wang

21 October 2026 at 01:00

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11185-0

A free-form additive manufacturing method that uses alternating and pulsed heat inputs is described for fabricating metre-tall, centimetre-diameter single crystals of Ti-6Al-4V, as well as hard-to-process refractory metals, including W, Mo, Nb and MoNb alloys.

Spatial distribution of the proteome in the human body and in cancers

Nature

By: Liang Yue · Wenhao Jiang · Sainan Li · Meng Luo · Ning Fan · Xiaolu Zhan · Rui Sun · Honghan Cheng · Zhangzhi Xue · Tong Liu · Qianhe Zhou · Kexin Chen · Tian Lu · Fang Guo · Dongwei Li · Weigang Ge · Zongxiang Nie · Mengge Lyu · Jun A · Yingrui Wang · Yingdan Chen · Zhenhai Fu · Nan Xiang · Lu Li · Fengchao Yu · Guo Ci Teo · Alexey I. Nesvizhskii · Meng Wang · Michael P. Snyder · Ben C. Collins · Qi Xiao · Ruedi Aebersold · Fei Xu · Hui Yang · Sijia Zhang · Yi Han · Yi Zhu · Yong Ji · Yan Li · Tiannan Guo

17 June 2026 at 01:00

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10660-y

A spatially resolved map of the human proteome across a variety of healthy tissues and cancers provides wide-ranging insights in developmental biology and oncology, and could aid the identification of therapeutic targets and development of treatments for cancer.