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Cortex-wide imaging in naturally behaving mice with 1-gram wireless mesoscopes
Nature, Published online: 19 October 2026; doi:10.1038/s41586-026-11293-x
Cortex-wide imaging in naturally behaving mice with 1-gram wireless mesoscopes
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CRISPR–Cas regulates expression of embedded anti-phage defence systems
Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10833-9
CRISPR–Cas systems transcriptionally tune diverse innate defences using CRISPR RNA-like guides to balance antiviral protection with fitness, and hyperactivate these defences when compromised, establishing a layered bacterial ‘immunity guard’ network.
Towards the construction of a virtual yeast
Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10574-9
A virtual yeast, an artificial intelligence-driven agent for modelling eukaryotic cellular behaviours, is described.
Spatial distribution of the proteome in the human body and in cancers
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10660-y
A spatially resolved map of the human proteome across a variety of healthy tissues and cancers provides wide-ranging insights in developmental biology and oncology, and could aid the identification of therapeutic targets and development of treatments for cancer.
Efficient and accurate neural-field reconstruction using resistive memory
Nature, Published online: 10 June 2026; doi:10.1038/s41586-026-10646-w
A co-optimized AI hardware–software system using resistive-memory computing improves energy efficiency and parallelism for sparse signal reconstruction in imaging and three-dimensional vision applications.