Reading view

GRP75-dependent SIMPA mediates inter-organellar quality control

By: Fan Yu · Lingyu Jiang · Hanyu Liu · Song Yang · Yuan Yuan · Hongzhen Jin · Jinming Liu · Xi Liu · Yu Dong · Dongfeng Ren · Jie Kang · Yan Huang · Qi Meng · Feng Bai · Yanjun Li · Shuoguo Li · Huadong Liu · Wei Zhao · Jia Xiao · Quan Chen

21 October 2026 at 01:00

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-10733-y

Proteotoxic stress drives formation of GRP75-dependent protein aggregates that signal through mitochondria–ER contact sites to activate targeted quality-control pathways, enabling selective clearance of damaged proteins and preserving mitochondrial integrity.

Anion-decoupled electrolytes enable stable cycling and fast interfacial kinetics for calcium metal anodes

RSC - Energy Environment

By: Qi Meng · Zhen Zhan · Yiyuan Ma · Qi Qi · Yingkai Hua · Yuyang Yi · Jingya Yu · Mengcheng Wu · Jingjing Tang · Songhua Cai · Kang Cheung Chan · Zheng-Long Xu

2 April 2026 at 00:00

Energy Environ. Sci., 2026, 19,3203-3213
DOI: 10.1039/D5EE07317K, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Qi Meng, Zhen Zhan, Yiyuan Ma, Qi Qi, Yingkai Hua, Yuyang Yi, Jingya Yu, Mengcheng Wu, Jingjing Tang, Songhua Cai, Kang Cheung Chan, Zheng-Long Xu
An anion-decoupling strategy significantly accelerates Ca²⁺ transport and minimizes desolvation barriers. The resulting organic-rich SEI facilitates rapid Ca²⁺ diffusion and supports highly reversible Ca metal anodes.
The content of this RSS Feed (c) The Royal Society of Chemistry