As much as half of the human genome is composed of so-called "jumping genes." These DNA sequences can make copies of themselves that are inserted back into the genome at another location, playing a significant functional role in creating the diversity that drives evolution and in regulating how other genes are turned on or off.
Penn State study identifies new regulator of jumping genes
Researchers at Weill Cornell Medicine have identified a molecular pathway that contributes to the death of insulin-producing beta cells in the pancreas.
Blocking specific proteins protects beta cells om excessive cellular stress
Biological clocks coordinate the spatiotemporal organization of metabolism with diurnal time cues, and bulk-tissue RNA sequencing studies in mammals have revealed widespread circadian (about 24 h) gene expression in mice and non-human primates.
Study shows circadian rhythms vary across different cell types
A new paper from the Equality, Diversity and Inclusion Committee and the Early Career Network of the European Sleep Research Society warns that sleep health is becoming a growing public health challenge across Europe and is calling for coordinated action to protect it.
Researchers call for coordinated action to protect European sleep health
Chemotherapy selectivity is limited by systemic toxicity. pHβsensitive nanocarriers exploit tumor acidity as a release trigger but respond passively to a modest, heterogeneous gradient.
Glucose priming may improve tumor targeting for chemotherapy nanocarriers
Neurodevelopmental, psychiatric, and neurodegenerative disorders are traditionally studied separately yet show overlapping disturbances in neural regulation and resilience.
Women in the United States can expect to provide seven years of care over their lifetimes to aging family members or friends-up from six in 2011, University of Michigan research shows.
Women provide more lifetime elder care than men, study shows