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GRP75-dependent SIMPA mediates inter-organellar quality control

21 October 2026 at 01:00

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-10733-y

Proteotoxic stress drives formation of GRP75-dependent protein aggregates that signal through mitochondria–ER contact sites to activate targeted quality-control pathways, enabling selective clearance of damaged proteins and preserving mitochondrial integrity.

Dynamic localized domains of metallic glasses enable high-capacity SbBi anodes for potassium-ion batteries

28 April 2026 at 00:00

Energy Environ. Sci., 2026, 19,3586-3597
DOI: 10.1039/D6EE01770C, Paper
Xi Liu, Xinying Wang, Yang Liu, Ao Jia, Yi Peng, Wanjie Gao, Bingyan Song, Kunming Yang, Jiarui He, Yuping Wu
As the cycle progresses, the Cu2Sb@SbBi2 anode forms a metallic glasses (MG) interface at the heterojunction, which enables rapid ion transport. The MG at this interface undergoes dynamic, localized changes as the potential varies.
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