<i>De novo</i> design of enantioselective artificial metalloenzyme photocatalysts
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11317-6
De novo design of enantioselective artificial metalloenzyme photocatalystsNature, Published online: 21 October 2026; doi:10.1038/s41586-026-11317-6
De novo design of enantioselective artificial metalloenzyme photocatalystsNature, Published online: 21 October 2026; doi:10.1038/s41586-026-11252-6
Author Correction: Catalyst-free, microdroplet-mediated waste plastic conversion to diacidsNature, Published online: 21 October 2026; doi:10.1038/d41586-026-03161-5
Tolullah Oni has developed a platform to transfer the intellectual capital of African diaspora scholars back to the continent.Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03355-x
The United Nations’ latest climate report is a stark reminder that limiting warming to the safest levels is now likely out of reach.Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03360-0
Archaeologists identified skull fragments from China as belonging to this group of ancient human relatives.Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03375-7
Researcher and policy adviser who championed tests and treatments for genetic diseases.Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03311-9
Money from the world’s increasingly prosperous technology entrepreneurs has been flooding into biomedical research. Is it changing how science is done?Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11096-0
Now that hyperacute rejection of pig xenografts can be reliably prevented, subtler immune-mediated graft injuries have emerged that conventional diagnostics often miss; a multimodal precision diagnostic framework is proposed to detect these injuries earlier, guide personalized immunosuppression and inform future gene editing strategies.Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11145-8
Salt marsh platforms resist erosion under extreme waves, but vegetation damage reduces wave attenuation; substantial wave attenuation by vegetation is mainly limited to low-energy marsh coasts with waves below 1 m.Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11152-9
A multi-tissue signalling system links cold temperature to enhanced longevity and proteostasis in Caenorhabditis elegans.Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11188-x
Experimental and modelling data indicate that WEE1 promotes re-entry of quiescent cells into the cell cycle, potentially explaining the toxic side effects of WEE1 inhibitors in cancer therapies.Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11207-x
Methanoglobus dolicholipophagus AA-75 is a thermophilic archaeon isolated from a Chinese petroleum reservoir that converts methanol into methane, carbon dioxide and acetate, and uses saturated and unsaturated fatty acids to produce methane.Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11179-y
An environment-regulated state is identified across multiple cell types at the root tip, revealing a shared dichotomy between cells with and without this state.Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11186-z
CD51+ astrocytes promote synapse formation in the developing cortex, circuit plasticity in the hippocampus and circuit remodelling after stroke.Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11165-4
Genetic and proteomic analyses in human neurons and mouse models of Angelman syndrome (AS) show that loss of the ubiquitin ligase UBE3A leads to an overabundance of asparagine synthetase, and that this is linked with many AS phenotypes.Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11184-1
The structure of PCDH1 bound to the ANDV spike defines the structural determinants of hantavirus–receptor recognition.Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-10733-y
Proteotoxic stress drives formation of GRP75-dependent protein aggregates that signal through mitochondria–ER contact sites to activate targeted quality-control pathways, enabling selective clearance of damaged proteins and preserving mitochondrial integrity.Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11205-z
Pinal, a 16-billion-parameter artificial intelligence model, designs functional proteins from natural-language descriptions, demonstrating experimentally validated activities and improved CO2-fixation product yields without iterative optimization.Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11172-5
All-antiferromagnetic tunnel junctions can display both a large TMR and a reciprocal switching effect, octupole-driven spin-transfer torque, enabling nanoscale magnetic memory and potentially room-temperature terahertz spintronic devices.Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11168-1
Fifteen years of atmospheric CO2 measurements show that the Amazon carbon sink is weakening, with fires, deforestation and climate stress driving increasingly high carbon emissions.